Scientist II Purification Process Design

Key Responsibilities

• Drive all aspects of purification process development, characterization, and technology transfer to cGMP manufacturing for hybrid and continuous processes
• Serve as an internal technical resource for cGMP manufacturing and Process Design
• Communicate scientific information, experimental plans, and data to internal project teams, senior management, and technology development collaborators
• Design, execute, and analyze statistically designed experiments (DOE)
• Author work instructions, reports, and slides summarizing, organizing, and interpreting experiment results
• Drive technology development for process intensification and continuous manufacturing

Requirements

Education

Master's degree in engineering, Biochemistry, Biotechnology or related field, or PhD

Experience

7+ years with Master's degree or 3+ years with PhD in Biosimilars for mammalian derived purification process

Required Skills

• Preparative chromatography
• AKTA systems operation
• Filtration operations
• Bench-scale dead-end filtration
• Viral filtration
• UF/DF
• Downstream process development for mammalian cell line based protein
• Buffer compounding
• Scale-up strategy
• Experimental design and analysis
• Microsoft Office applications
• Strong written and verbal communication in English
• Ability to work independently and in teams