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Computational Biologist - Neurogenomics and Somatic Mosaicism - Job Opportunity at Institut Imagine

Paris, France
Contract
Mid-level
Posted: March 1, 2025
On-site
EUR 45,000-65,000 annually based on French research institution scales and experience level

Benefits

ERC StG funded position with 3+1 year duration
Access to state-of-the-art sequencing technologies
Collaborative research environment with top scientists
Integration with Imagine Institute bioinformatic hub
Work within prestigious European research center

Key Responsibilities

Analyze deep bulk whole-genome sequencing data
Process and interpret single-cell multi-omics data
Apply and optimize computational tools for genomic analysis
Collaborate with geneticists, developmental biologists and clinicians
Contribute to research projects studying somatic mosaicism in neurodevelopment
Participate in international research initiatives

Requirements

Education

Master degree or PhD in Computational Biology/Bioinformatics/Biostatistics or similar

Required Skills

Strong programming skills (R, Python, Bash) Good communication skills Proficiency in English General interest in neurogenomics and neurodevelopment
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Sauge AI Market Intelligence

Industry Trends

Rising importance of single-cell genomics in neurodevelopmental research is creating increased demand for computational specialists with multi-omics expertise Integration of clinical and research data is becoming crucial in translational medicine, particularly in rare genetic diseases Growing focus on somatic mosaicism research is opening new career paths in neurogenomics

Role Significance

Typically part of a specialized research team of 5-10 members including PI, postdocs, and technical staff
Mid to senior-level position with significant research autonomy and collaborative responsibilities

Key Projects

Development of computational pipelines for somatic variant analysis Integration of single-cell multi-omics data for neurodevelopmental studies Collaborative projects with clinical teams for translational research

Success Factors

Strong foundation in computational biology and statistics Ability to bridge wet-lab and computational research Excellent communication skills for cross-disciplinary collaboration Self-directed learning and research initiative

Market Demand

High demand with limited qualified candidate pool due to specialized skill requirements in both computational biology and neuroscience

Important Skills

Critical Skills

Advanced programming skills for complex genomic data analysis Statistical expertise for biological data interpretation Communication skills for cross-disciplinary collaboration

Beneficial Skills

Experience with cloud computing platforms Knowledge of machine learning applications in genomics Understanding of clinical research protocols

Unique Aspects

Direct access to clinical data and patient cohorts
Integration of cutting-edge sequencing technologies with clinical research
Strong potential for high-impact publications
Position funded by prestigious ERC grant

Career Growth

2-4 years in position before advancement, with potential for academic career progression or industry transition

Potential Next Roles

Principal Investigator Senior Bioinformatician in Industry Research Team Leader Computational Biology Director

Company Overview

Institut Imagine

Premier European research center for genetic diseases with strong integration between research and clinical practice

Leading institution in genetic disease research with significant international recognition
Central role in French biomedical research landscape with strong international collaborations
Academic research environment with emphasis on collaboration and innovation
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