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PhD Position - Enzymatic Synthesis of Valuable Hydroxyketones - Job Opportunity at Université Clermont Auvergne

Aubière, France
Contract
Entry-level
Posted: March 25, 2025
On-site
EUR 25,000-30,000 per year (standard French doctoral contract)

Benefits

Doctoral contract funding
Academic research environment
Access to advanced laboratory facilities
Collaboration opportunities with ICCF platform

Key Responsibilities

Design and execute enzymatic synthesis protocols
Conduct molecular modeling and mutagenesis experiments
Perform enzyme activity screening and optimization
Characterize synthesized compounds using advanced analytical techniques
Manage research project timeline and deliverables
Collaborate with microbiology and modeling teams

Requirements

Education

Master 2 or Engineering degree

Required Skills

Organic chemistry Biochemistry/enzymology Molecular modeling Analytical techniques (NMR, MS, GC-MS) Enzyme purification Spectrophotometry
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Sauge AI Market Intelligence

Industry Trends

Growing demand for green chemistry solutions in pharmaceutical manufacturing Increased focus on enzymatic synthesis for sustainable production methods Rising importance of stereoselective synthesis in drug development Expansion of biocatalysis applications in fine chemical production

Role Significance

Part of a specialized research group, typically 5-10 members including PI, post-docs, and other PhD students
Entry-level research position with significant technical responsibility and project ownership

Key Projects

Development of novel enzymatic synthesis pathways Optimization of biocatalytic processes Green chemistry implementation in pharmaceutical manufacturing

Success Factors

Strong foundation in both organic chemistry and biochemistry Ability to integrate computational and experimental approaches Excellent analytical and problem-solving skills Strong documentation and scientific communication abilities

Market Demand

High demand for specialists in enzymatic synthesis and green chemistry, particularly in pharmaceutical and fine chemical industries

Important Skills

Critical Skills

Expertise in enzyme engineering and characterization Understanding of stereoselective synthesis principles Proficiency in analytical techniques

Beneficial Skills

Programming skills for molecular modeling Experience with scale-up processes Knowledge of industrial applications

Unique Aspects

Integration of green chemistry principles with enzymatic synthesis
Cross-disciplinary approach combining molecular modeling and experimental methods
Focus on industrially relevant hydroxyketone synthesis

Career Growth

3-year doctoral program with potential for academic or industry transition upon completion

Potential Next Roles

Post-doctoral researcher Industrial R&D scientist Process development specialist Biotechnology researcher

Company Overview

Université Clermont Auvergne

Major French public research university with strong emphasis on fundamental sciences

Well-established academic institution with significant research funding and international collaborations
Leading research center in the Auvergne-Rhône-Alpes region
Collaborative academic environment with focus on innovation and scientific excellence
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