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Postdoctoral Fellow / Research Associate - Clinical Translation of Anti-Microbial Therapy for Eye Infections - Job Opportunity at Centre for Eye and Vision Research Ltd

Hong Kong Science Park, Hong Kong
Contract
Mid-level
Posted: June 27, 2025
On-site
HKD 23,000-45,000 per month

Benefits

Access to cutting-edge mass spectrometry technologies providing exposure to state-of-the-art research infrastructure that positions candidates at the forefront of analytical science
Direct collaboration opportunities with experimental scientists and clinicians offering invaluable cross-disciplinary experience that enhances research impact and career development
Living allowance of HKD 10,000 for Postdoctoral Fellows supplementing base salary and acknowledging cost of living considerations in Hong Kong
International research collaboration experience through partnership between Hong Kong Polytechnic University and University of Waterloo expanding global professional networks
InnoHK government funding support ensuring research stability and access to substantial resources for innovative projects

Key Responsibilities

Lead development and application of computational methods to analyze multi-omics data including next-generation sequencing, mass spectrometry-based proteomics, and spatial transcriptomics, directly contributing to breakthrough therapeutic discoveries
Drive collaborative research initiatives with wet-lab scientists and clinical researchers to validate computational findings and generate experimental data that advances clinical translation objectives
Execute project management responsibilities while mentoring students and contributing to grant applications, building essential leadership skills for academic and industry career advancement
Contribute to commercialization efforts of novel combination drug-based therapies targeting antibiotic-resistant eye infections, addressing a critical global health challenge
Participate in interdisciplinary team projects that integrate computational and mass spectrometry technologies, positioning the research for maximum clinical and commercial impact

Requirements

Education

Doctoral degree for Postdoctoral Fellow position or Master's degree for Research Associate position in mass spectrometry, Proteomics, Cell Biology, Molecular Biology, Bioinformatics, or related discipline

Experience

Not specified

Required Skills

Solid understanding of biology with ability to effectively communicate with biologists and clinical researchers Strong passion for science and ability to work independently Excellent analytical skills Computational methods for multi-omics data analysis Next-generation sequencing (NGS) analysis Mass spectrometry-based proteomics Spatial transcriptomics

Certifications

Qualification from top 100 institutions for STEM-related subjects in QS/Shanghai Jiao Tong University/Times Higher Education world university rankings for overseas graduates
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Sauge AI Market Intelligence

Industry Trends

The ophthalmic therapeutics market is experiencing rapid growth driven by increasing prevalence of eye diseases and aging populations globally, with antimicrobial resistance presenting a critical challenge that requires innovative solutions like the novel combination therapies being developed in this role. Computational biology and multi-omics integration are becoming essential drivers in drug discovery and clinical translation, with mass spectrometry-based approaches gaining particular prominence for their ability to provide comprehensive molecular insights that traditional methods cannot achieve. The convergence of academic research institutions with government-backed innovation initiatives like InnoHK represents a growing trend toward public-private partnerships that accelerate translational research and bridge the gap between laboratory discoveries and clinical applications.

Salary Evaluation

The offered salary range of HKD 23,000-45,000 monthly (approximately USD 35,000-70,000 annually including allowances) is competitive for the Hong Kong research market, particularly considering the government funding support and access to cutting-edge facilities, though it may be below industry standards for similar computational biology roles in pharmaceutical companies.

Role Significance

Typical team structure would involve 5-8 researchers including wet-lab scientists, computational biologists, and clinical collaborators, with the appointee serving as a key bridge between computational and experimental components of the research program.
This represents a mid-level research position with significant growth potential, offering substantial autonomy in computational method development while providing mentoring responsibilities that indicate preparation for senior research leadership roles in academic or industry settings.

Key Projects

Multi-omics data integration projects combining genomics, proteomics, and metabolomics data to identify novel therapeutic targets Clinical biomarker discovery initiatives using mass spectrometry approaches to validate computational predictions Drug resistance mechanism studies employing spatial transcriptomics to understand tissue-level responses to antimicrobial treatments

Success Factors

Strong computational skills combined with biological intuition to generate meaningful insights from complex multi-omics datasets that can guide experimental validation and clinical translation efforts. Excellent communication abilities to effectively collaborate across disciplines and translate computational findings into actionable experimental hypotheses for wet-lab colleagues and clinical researchers. Project management capabilities and mentoring skills that demonstrate readiness for research leadership roles while contributing to grant writing and strategic research planning activities. Adaptability to work in an international collaborative environment with researchers from different cultural and academic backgrounds while maintaining high productivity and research quality standards.

Market Demand

High demand exists for professionals with computational biology and mass spectrometry expertise, particularly those who can bridge wet-lab and dry-lab research, as the pharmaceutical and biotechnology industries increasingly rely on multi-omics approaches for drug discovery and development.

Important Skills

Critical Skills

Multi-omics data analysis capabilities are absolutely essential as the role centers on integrating diverse high-throughput datasets to generate clinically actionable insights, requiring expertise in handling large-scale genomics, proteomics, and transcriptomics data with appropriate statistical and computational methods. Mass spectrometry knowledge is fundamental given the lab's focus on proteomics-based approaches and the availability of cutting-edge MS technologies, requiring understanding of both analytical principles and data interpretation methods specific to biological applications. Interdisciplinary communication skills are crucial for success in translating computational findings to experimental biologists and clinical researchers, requiring ability to present complex analytical results in accessible formats that guide experimental design and clinical decision-making.

Beneficial Skills

Project management experience would significantly enhance career progression opportunities, particularly given the mentoring responsibilities and grant application involvement that prepare candidates for future research leadership roles. Clinical research exposure would provide valuable context for understanding the translational aspects of the work and improving the clinical relevance of computational analyses and experimental design recommendations. Commercialization awareness would be highly valuable given the center's focus on technology transfer and the specific goal of commercializing novel antimicrobial therapies, providing insights into intellectual property considerations and market requirements.

Unique Aspects

Direct involvement in clinical translation of breakthrough antimicrobial therapies addressing the critical global challenge of antibiotic resistance in ophthalmology, providing opportunities to contribute to solutions with immediate clinical relevance.
Access to world-class mass spectrometry facilities and computational infrastructure through the InnoHK initiative, offering research capabilities that rival those found at top-tier pharmaceutical companies and academic institutions.
International collaborative framework combining Canadian and Hong Kong research expertise, providing unique exposure to different research approaches and expanding global professional networks in vision science and computational biology.
Government funding stability through the Research Talent Hub program ensuring consistent support for innovative research without the typical uncertainties associated with traditional grant funding cycles.

Career Growth

Career advancement to senior roles typically occurs within 3-5 years for high-performing researchers, with the international collaboration experience and clinical translation focus providing accelerated pathways to leadership positions.

Potential Next Roles

Senior Research Scientist positions in pharmaceutical or biotechnology companies focusing on computational drug discovery and development Principal Investigator roles in academic institutions leading independent research programs in computational biology and therapeutic development Director-level positions in government research agencies or innovation hubs overseeing translational research initiatives

Company Overview

Centre for Eye and Vision Research Ltd

Centre for Eye and Vision Research Ltd operates as a prestigious InnoHK research center representing a strategic partnership between Hong Kong Polytechnic University and University of Waterloo, positioning it at the forefront of vision research innovation with substantial government backing and international academic credibility.

As one of the select InnoHK centers, CEVR holds a prominent position in the Hong Kong innovation ecosystem with access to significant funding and state-of-the-art facilities, competing directly with leading international research institutions in ophthalmology and vision science.
The organization serves as a key hub for Asia-Pacific vision research while maintaining strong connections to North American research networks through the University of Waterloo partnership, providing unique opportunities for global research collaboration and knowledge exchange.
The research environment emphasizes interdisciplinary collaboration and clinical translation with a strong focus on commercialization and real-world impact, typical of government-backed innovation centers that balance academic rigor with practical application goals.
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