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Scientist/Associate Scientist - Personalized Genomic Therapeutics - Job Opportunity at St. Jude Children's Research Hospital

Memphis, US
Full-time
Senior
Posted: March 12, 2025
On-site
USD 86,320 - 154,960 per year

Benefits

World-class research facilities and state-of-the-art technologies
Collaborative bench-to-bedside environment
Career development and advancement opportunities
Comprehensive healthcare benefits package
Opportunity to directly impact pediatric healthcare outcomes

Key Responsibilities

Lead development of personalized genomic and oligonucleotide therapeutics for GEMINI program cases
Design and execute IND-enabling experiments using patient-derived platforms
Develop and implement laboratory automation workflows for scalable oligonucleotide screening
Manage preclinical operations and documentation for therapeutic approval processes
Collaborate with internal and external stakeholders on strategic initiatives

Requirements

Education

Bachelor's degree in a relevant scientific area is required

Experience

Scientist: 8 years experience (BS), 6 years (MS), 3 years (PhD); Associate Scientist: 7+ years (BS), 5+ years (MS), 2+ years (PhD)

Required Skills

RNA therapeutics and genomics expertise High-throughput screening techniques Laboratory automation and robotics Patient-derived cellular platforms Documentation and protocol development Scientific communication and presentation
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Sauge AI Market Intelligence

Industry Trends

The personalized genomic therapeutics field is experiencing rapid growth, particularly in rare disease treatment development Increased focus on pediatric-specific therapeutic approaches is driving demand for specialized expertise Integration of automation and high-throughput screening is becoming standard in therapeutic development Growing emphasis on patient-derived models and personalized medicine approaches

Salary Evaluation

The offered salary range aligns with market standards for senior scientific roles in biotech, considering the specialized nature of personalized genomics and the institutional prestige

Role Significance

Likely part of a specialized core facility team of 5-10 scientists with supporting technical staff
Senior technical position with significant project leadership responsibilities and direct impact on therapeutic development

Key Projects

Development of personalized genomic therapies for rare pediatric disorders Implementation of automated screening platforms IND-enabling studies for novel therapeutic candidates Patient-specific therapeutic development programs

Success Factors

Deep understanding of RNA therapeutics and genomic medicine Ability to bridge research and clinical applications Strong project management and documentation skills Experience with regulatory requirements and IND processes Effective collaboration with multi-disciplinary teams

Market Demand

Very high demand due to specialized skill combination of genomics, RNA therapeutics, and automation expertise

Important Skills

Critical Skills

RNA therapeutics expertise - essential for therapeutic design and optimization High-throughput screening - crucial for efficient candidate evaluation Patient-derived cell work - fundamental to personalized medicine approach

Beneficial Skills

Project management experience Regulatory knowledge Clinical trial expertise Automation programming skills

Unique Aspects

Direct involvement in cutting-edge personalized medicine development
Rare opportunity to work on pediatric-focused genomic therapeutics
Integration of multiple advanced technological platforms
Clear path from research to clinical application

Career Growth

3-5 years to advance to senior program leadership roles, depending on project success and organizational growth

Potential Next Roles

Core Facility Director Senior Research Scientist Therapeutic Development Program Leader Clinical Research Director

Company Overview

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is a world-leading pediatric research institution with a unique focus on catastrophic childhood diseases

Premier institution in pediatric research and treatment, particularly in rare and genetic diseases
Major employer in Memphis biotech sector with global research impact
Mission-driven environment with strong emphasis on innovation and collaboration
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