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Scientist - BioPharma R&D - Job Opportunity at AstraZeneca

Cambridge, United Kingdom
Full-time
Mid-level
Posted: January 27, 2025
On-site
GBP 45,000-65,000 per year based on Cambridge biotech market rates and role requirements

Benefits

Competitive company pension scheme with market-leading contribution rates
Flexible employee benefits fund with comprehensive coverage
Share Save Plans for long-term wealth building
Performance-based recognition and bonus scheme
Holiday purchase options and flexible time off policies
Comprehensive healthcare and wellness programs

Key Responsibilities

Lead DNA plasmid design and construction for mammalian protein expression systems
Develop and optimize high-throughput molecular cloning methodologies
Execute protein expression experiments using advanced mammalian cell culture systems
Analyze and interpret complex biological data to guide drug discovery decisions
Collaborate with cross-functional teams to advance biologics development
Maintain detailed documentation and contribute to regulatory submissions
Train and mentor junior team members and students
Ensure compliance with safety and quality standards

Requirements

Education

Bachelor/Master of Science degree in life sciences

Required Skills

DNA plasmid design and construction Mammalian protein expression Molecular cloning Sequence analysis Gene and protein expression knowledge Professional communication Attention to detail Team collaboration Scientific curiosity
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Sauge AI Market Intelligence

Industry Trends

Increasing focus on next-generation biologics and novel therapeutic modalities Growing adoption of automated high-throughput screening platforms in biopharma R&D Rising importance of multi-modal therapeutic approaches in drug development Expansion of personalized medicine driving demand for advanced protein engineering

Role Significance

Typically part of a 5-10 person molecular biology team within larger R&D organization of 50-100 scientists
Mid-level scientific position with significant technical autonomy and project influence

Key Projects

Development of novel antibody therapeutics Platform optimization for protein expression Technology transfer to manufacturing scale Process validation and optimization studies

Success Factors

Strong foundation in molecular biology techniques and protein expression systems Ability to work independently while contributing to team objectives Excellence in documentation and regulatory compliance Innovative problem-solving approach to technical challenges Strong communication skills for cross-functional collaboration

Market Demand

High demand role with strong growth trajectory due to expanding biologics pipeline across the industry and increasing focus on novel therapeutic modalities

Important Skills

Critical Skills

Molecular biology expertise with focus on mammalian expression systems Experience with high-throughput methodologies Strong analytical and problem-solving capabilities

Beneficial Skills

Automation experience Flow cytometry knowledge Experience with different sequencing methodologies Understanding of GMP requirements

Unique Aspects

Access to cutting-edge technology and research facilities
Opportunity to work in one of the world's leading biotech hubs
Exposure to diverse biological modalities and therapeutic areas
Strong emphasis on personal development and career progression

Career Growth

2-4 years in role typical before advancement, depending on performance and project success

Potential Next Roles

Senior Scientist Principal Scientist Team Leader Technical Specialist

Company Overview

AstraZeneca

Global biopharmaceutical leader with strong focus on innovative medicines and significant R&D investment

Top-tier pharmaceutical company with robust pipeline and strong market presence
Cambridge site represents one of three strategic global R&D centers, indicating significant investment and growth potential
Science-led environment with high emphasis on innovation, collaboration, and professional development
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