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Senior Computational Biologist - Job Opportunity at Grafton Biosciences Inc

Remote, US
Full-time
Senior
Posted: April 13, 2025
Remote
USD 150,000 - 220,000 per year

Benefits

Comprehensive Health Insurance with comprehensive medical coverage
Dental Insurance with preventive and major procedure coverage
Vision Insurance supporting eye health and corrective needs
401(k) Retirement Plan indicating long-term investment in employees
Flexible Paid Time Off Policy supporting work-life balance

Key Responsibilities

Lead computational strategies for novel therapeutic target identification through multi-omics data analysis
Drive pathway and network analysis using advanced bioinformatics tools for disease understanding
Perform structural biology interpretation to inform drug design and mutation impact
Develop and maintain robust computational pipelines for reproducible analysis
Integrate and analyze large-scale multi-omics datasets for actionable insights

Requirements

Education

PhD in Computational Biology, Bioinformatics, Systems Biology, Biophysics, Computer Science, or related field

Experience

5+ years of relevant post-doctoral or industry experience

Required Skills

High agency and autonomy in fast-paced environments Expertise in computational target identification Pathway and network analysis proficiency Strong understanding of protein structure and computational tools Multi-omics data integration experience Programming proficiency (Python, R) Linux/Unix environment expertise Statistical analysis capabilities Problem-solving and critical thinking Strong communication skills
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Sauge AI Market Intelligence

Industry Trends

The convergence of AI and computational biology is reshaping drug discovery, with companies increasingly leveraging machine learning for target identification and validation Multi-omics integration is becoming critical as the industry moves towards more holistic understanding of disease mechanisms Remote work adoption in biotech is accelerating, particularly for computational roles, expanding talent access

Salary Evaluation

The offered salary range of $150,000-$220,000 is competitive for senior computational biology roles, particularly considering the remote nature and startup environment. This range aligns with market rates for similar positions at biotech startups.

Role Significance

Likely part of a small but growing technical team of 5-10 specialists, typical for an early-stage biotech startup
Senior individual contributor role with significant autonomy and potential for technical leadership in driving drug discovery initiatives

Key Projects

Novel therapeutic target identification and validation programs Development of integrated multi-omics analysis pipelines Structure-based drug design support initiatives Machine learning model development for biological predictions

Success Factors

Ability to bridge computational methods with biological insights Strong independent research capabilities and scientific creativity Excellent cross-functional collaboration skills Balance of technical expertise with business impact understanding

Market Demand

Very high demand with growing competition for talent as more biotech companies integrate computational approaches into their drug discovery processes

Important Skills

Critical Skills

Multi-omics data integration expertise is essential for developing comprehensive disease understanding Strong programming skills particularly in Python/R for building robust analysis pipelines Protein structure analysis capabilities for drug design support

Beneficial Skills

Machine learning expertise for advanced biological data analysis Cloud computing experience for scalable computation Drug development process understanding

Unique Aspects

Unusual combination of biotech and space exploration in company mission
Strong emphasis on autonomous work and self-direction
Integration of multiple advanced technologies including ML and synthetic biology

Career Growth

2-4 years typical progression timeline in a growth-stage startup environment

Potential Next Roles

Principal Scientist Director of Computational Biology Head of Drug Discovery Informatics Chief Scientific Officer

Company Overview

Grafton Biosciences Inc

Early-stage biotech startup focusing on innovative approaches to disease detection and treatment, with a unique mission connecting human health to space exploration

Emerging player in the competitive biotech startup landscape, differentiated by its integration of multiple cutting-edge technologies
Remote-first organization likely headquartered in a major biotech hub
Fast-paced, innovation-focused environment with emphasis on autonomy and impact
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