Upstream Manufacturing Scientist - Job Opportunity at PE Global

Dunboyne, Ireland
Contract
Senior
Posted: May 14, 2025
On-site
EUR 65,000 - 85,000 annually based on Irish biotech market rates for senior scientific roles

Benefits

11-month contract opportunity
Experience with state-of-the-art single-use facilities
Professional development through cross-functional exposure
Weekend shift premium likely applies

Key Responsibilities

Lead upstream manufacturing process optimization and scale-down model development
Drive technical transfer and new product introduction initiatives
Conduct experimental design and data analysis for process improvement
Provide specialist support for troubleshooting and non-routine analysis
Ensure GMP compliance and quality standards
Collaborate with global technical teams on product robustness
Author technical documentation and SOPs

Requirements

Education

BS with 5+ years, MS with 3+ years, or PhD in biotechnology, biochemistry, pharmacy, or process engineering

Experience

3-5 years depending on education level

Required Skills

Biologics drug substance operations Upstream and downstream processing Analytical testing Process development Tech transfer GMP environment experience Lean Six Sigma Problem-solving Team collaboration Technical writing Project management
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Sauge AI Market Intelligence

Industry Trends

Increasing adoption of single-use technology in biomanufacturing reflects industry-wide shift toward flexible, scalable production systems Growing demand for MS&T specialists due to rising complexity in biologics manufacturing and regulatory requirements Trend toward integrated upstream/downstream process optimization requiring hybrid skill sets

Role Significance

Likely part of a 5-10 person MS&T team within larger manufacturing organization
Senior technical position with significant influence on process optimization and technology transfer

Key Projects

New product introduction and tech transfer initiatives Process optimization and scale-down model development Manufacturing troubleshooting and investigation support Quality system enhancement and regulatory compliance projects

Success Factors

Deep technical expertise in upstream bioprocessing Strong analytical and problem-solving capabilities Effective cross-functional collaboration skills Balance of technical excellence with practical implementation Ability to work independently while supporting team objectives

Market Demand

High demand with significant growth projected due to expanding biologics pipeline and manufacturing capacity in Ireland

Important Skills

Critical Skills

Upstream bioprocessing expertise essential for core role responsibilities Project management capabilities crucial for coordinating complex technical initiatives Communication skills vital for cross-functional effectiveness

Beneficial Skills

Downstream processing knowledge valuable for integrated process understanding Quality systems experience helpful for regulatory compliance Data analysis and DOE expertise advantageous for process optimization

Unique Aspects

Opportunity to work with state-of-the-art single-use manufacturing technology
Strong focus on technical leadership in process optimization
Balanced mix of hands-on laboratory work and strategic process improvement

Career Growth

2-3 years in role typical before advancement, depending on performance and organizational growth

Potential Next Roles

Principal Scientist Technical Lead Manufacturing Science Director Process Development Manager

Company Overview

PE Global

Contract role through PE Global for a leading biopharmaceutical manufacturer in Ireland's growing biotech sector

Position at a significant manufacturing site within Ireland's robust pharmaceutical manufacturing network
Part of Ireland's strategic biopharma manufacturing hub, benefiting from strong industry presence and government support
Professional environment with emphasis on technical excellence, quality focus, and cross-functional collaboration
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